Wetzel Chemistry Consulting, LLC

Home Services Qualifications Contact Us Patent Law Tutorial

“…[T]he market rewards progress in clinical development, and until clinical development begins, everything is worth about the same – not very much.” – Dennis P. Schafer, CEO, Curry Pharmaceuticals & founder of 8 biotechnology companies*

Below are some ways in which our clients have benefited from our services:

In Drug Discovery:

Several chemical series were prioritized according to their potential to yield drug-like leads for an anti-cancer target
The binding mode, structure-activity relationships and likely sites of off-target binding were clarified for two leading chemical series
Predicted off-target binding was experimentally verified for several key cross-reactivity sites
Testing strategies were designed and implemented for efficient prioritization of new compounds and minimization of off-target interactions
New analogs were designed for synthesis
Patent applications with accurate technical descriptions and appropriate claim scope were filed

In Drug Development:

Technical challenges were solved in active pharmaceutical ingredient (API) synthesis
API manufacturing costs were reduced
Toxic and environmentally hazardous chemistry was eliminated from an API synthetic process
Chemistry, Manufacturing and Controls (CMC) documents were prepared in support of two NDA filings
Concerns raised by regulatory agencies were successfully addressed through research, documentation and argumentation

How can we help you? Read more about our Services or Contact Us to discuss your needs.

Helping startup pharmaceutical companies reach all-important clinical milestones is our core business. With 16 years experience in the biotech / pharmaceutical industry in projects ranging from target discovery to clinical development, Wetzel Chemistry Consulting, LLC can help you discover and bring new drugs to the market. Our areas of expertise include:

Organic, Medicinal and Analytical Chemistry
Logistics, Automation and Information Management
Chemistry Manufacturing and Controls (CMC)
Intellectual Property

“Thus, in accord with our settled practice we construe the claim as written, not as the patentees wish they had written it.” – Court of Appeals for the Federal Circuit in Chef America, Inc. v. Lamb-Weston, Inc., 358 F.3d 1371 (Fed. Cir. 2004). Read more …

How valuable are your patents? The answer depends heavily on how well they are written. Court records contain numerous examples in which poor quality patent writing resulted in the loss of millions of dollars in value. Even a single poorly chosen word can invalidate a claim. Wetzel Chemistry Consulting, LLC can work with your inventors and patent attorneys to ensure that your chemistry patent applications are crafted with skill and care. We have extensive experience in writing chemistry patent applications and a reputation for getting the details right. Click here to read more about how we can help.

*Dennis P. Schafer and his companies are not affiliated with Wetzel Chemistry Consulting, LLC.

John M Wetzel, PhD and Wetzel Chemistry Consulting, LLC are not affiliated with John Wetzel, co-author of Chemistry for Christian Schools.